STATISTICIAN’S APPRENTICE: AN EXPECTED STATISTICAL PACKAGE OF THE NEXT GENERATION

Expected Next-Generation Drugs

BIGpre: A Quality Assessment Package for Next-Generation Sequencing Data

The emergence of next-generation sequencing (NGS) technologies has significantly improved sequencing throughput and reduced costs. However, the short read length, duplicate reads and massive volume of data make the data processing much more difficult and complicated than the first-generation sequencing technology. Although there are some software packages developed to assess the data quality, t...

Seq2pathway: an R/Bioconductor package for pathway analysis of next-generation sequencing data

UNLABELLED Seq2pathway is an R/Python wrapper for pathway (or functional gene-set) analysis of genomic loci, adapted for advances in genome research. Seq2pathway associates the biological significance of genomic loci with their target transcripts and then summarizes the quantified values on the gene-level into pathway scores. It is designed to isolate systematic disturbances and common biologic...

Genome analysis Seq2pathway: an R/Bioconductor package for pathway analysis of next-generation sequencing data

Summary: Seq2pathway is an R/Python wrapper for pathway (or functional gene-set) analysis of genomic loci, adapted for advances in genome research. Seq2pathway associates the biological significance of genomic loci with their target transcripts and then summarizes the quantified values on the gene-level into pathway scores. It is designed to isolate systematic disturbances and common biological...

girafe – an R/Bioconductor package for functional exploration of aligned next-generation sequencing reads

UNLABELLED The R/Bioconductor package girafe facilitates the functional exploration of alignments of sequence reads from next-generation sequencing data to a genome. It allows users to investigate the genomic intervals together with the aligned reads and to work with, visualise and export these intervals. Moreover, the package operates within and extends the ever-growing Bioconductor framework ...